High nuclear MSK1 is associated with longer survival in breast cancer patients.

CONCLUSIONS: High MSK1 is associated with improved breast cancer-specific survival in early stage invasive breast cancer patients, and has additional prognostic value in HER2-negative and non-basal like disease. Although not an independent marker of outcome, we believe such findings and significant associations with well-established negative prognostic factors (age, grade, Nottingham Prognostic Index, hormone receptor status, time to distant metastasis, recurrence and triple-negative/basal-like status) warrant further examination and validation in independent patient cohorts. PMID: 29327245 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29327245?dopt=Abstract

Source: Clinical Breast Cancer - January 11, 2018 Category: Cancer & Oncology Authors: Pu X, Storr SJ, Ahmad NS, Rakha EA, Green AR, Ellis IO, Martin SG Tags: J Cancer Res Clin Oncol Source Type: research