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The active glycosides from Urtica fissa rhizome decoction

This study revealed that glycosides played an important role in the therapeutic effects ofUrtica fissa rhizome.
Source: Journal of Natural Medicines - Category: Drugs & Pharmacology Source Type: research

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Conclusions: There was no clear correlation between RA-NPIs and pathologic corneal findings in our study. DMARDs treatment may help maintain corneal integrity in our patients and prevented collagenolytic manifestations of RA. Other medications such as azathioprine should be used carefully, as endothelial damage may potentially occur.
Source: Cornea - Category: Opthalmology Tags: Basic Investigation Source Type: research
ConclusionThe modified disc repositioning using an orthodontic screw via a mini preauricular approach provided a good functional outcome in all patients as assessed over a period of 6  months. However, the long-term functional sequel of the procedure and changes in the articular disc needs to be assessed.
Source: Journal of Maxillofacial and Oral Surgery - Category: ENT & OMF Source Type: research
This article is part of the European guidelines on perioperative venous thromboembolism prophylaxis. For details concerning background, methods, and members of the ESA VTE Guidelines Task Force, please, refer to: Samama CM, Afshari A, for the ESA VTE Guidelines Task Force. European guidelines on perioperative venous thromboembolism prophylaxis. Eur J Anaesthesiol 2018; 35:73–76. A synopsis of all recommendations can be found in the following accompanying article: Afshari A, Ageno W, Ahmed A, et al., for the ESA VTE Guidelines Task Force. European Guidelines on perioperative venous thromboembolism prophylaxis. Execu...
Source: European Journal of Anaesthesiology - Category: Anesthesiology Tags: Guidelines Source Type: research
ARTHRITIS symptoms include joint pain and inflammation. But, can cracking your knuckles or bending your fingers back until they click lead to the painful condition?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
(VIB (the Flanders Institute for Biotechnology)) An international team of researchers led by prof. Savvas Savvides (VIB-UGent Center for Inflammation Research) has unraveled a crucial aspect of the molecular basis of autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis and Crohn's disease. Focusing on the immunomodulatory cytokine IL-23 they discovered that its pro-inflammatory activity, which underlies a wide range of inflammatory diseases, critically depends on structural activation of the cytokine by its receptor, IL-23R.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Authors: Gwon SY, Rhee KJ, Sung HJ Abstract The risk of rheumatoid arthritis (RA), an autoimmune disease, in the elderly population increases along with that of atherosclerosis, cardiovascular disease, type 2 diabetes, and Alzheimer's disease. Identifying specific biomarkers for RA can clarify the underlying molecular mechanisms and can aid diagnosis and patient care. To this end, the present study investigated the genes and proteins that are differentially expressed in RA using a mouse collagen-induced arthritis (CIA) model. We performed gene microarray and proteome array analyses using blood samples from the mice...
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
Osteoarthritis could be treated more effectively in the future by dividing patients into two distinct disease groups, according to new research. TheArthritis Research UK-funded study, carried out by the University of Manchester, has discovered that the current definition of osteoarthritis may actually encompass two separate groups with different disease activity patterns, and that developing new treatments for both versions may be more effective than the current one-size-fits-all approach. Two different patterns of disease activity Published in the Annals of the Rheumatic Diseases, the research involved a mathematical anal...
Source: Arthritis Research UK - Category: Rheumatology Source Type: news
We report a case series of multi-failure 16 patients, successfully treated with secukinumab, a fully human monoclonal antibody that selectively neutralizes interleukin-17A, recently approved for the treatment of plaque psoriasis, psoriatic arthritis and ankylosing spondylitis. PMID: 29334270 [PubMed - as supplied by publisher]
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
CONCLUSION: Pediatric uveitis is challenging to diagnose and manage, with frequent and potentially severe complications. Most cases were bilateral, recurrent, and idiopathic. Prompt referral to uveitis-specialized centers and an appropriate systemic therapy are mandatory for good visual outcomes. PMID: 29333911 [PubMed - as supplied by publisher]
Source: Ocular Immunology and Inflammation - Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research
Follow me on Twitter @DrClaire Sore throats happen all the time in childhood — and most of the time, it’s nothing to worry about. Most of the time, they are simply part of a common cold, don’t cause any problems, and get better without any treatment. Sometimes, though, a sore throat can be a sign of a problem that might need medical treatment. Here are four examples: Strep throat. This infection, caused by a particular kind of streptococcus bacteria, is quite common. Along with a sore throat, children may have a fever, headache, stomachache (sometimes with vomiting), and a fine, pink rash that almost look...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Children's Health Cold and Flu Infectious diseases Parenting Source Type: blogs
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