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UK research investment analysis shows HIV and TB are relatively well funded, but pneumonia is neglected

UK research investment analysis shows HIV and TB are relatively well funded, but pneumonia is neglectedFri, 01/12/2018 - 15:05News blog
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news

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Publication date: Available online 13 December 2017 Source:Saudi Pharmaceutical Journal Author(s): Muneera S. Al-Saleem, Amani S. Awaad, Monerah R. Alothman, Saleh I. Alqasoumi The phytochemical screening, antimicrobial and antitumor activities of Calendula tripterocarpa, Centarea sinaica, Centaurea pseudosinaica, Koelpinia linearis, Plectranthus arabicus, Plectranthus asirensis and Tripleurospermum auriculatum determined. The best antibacterial activity; 41.8 ± 0.23 mm, 39.7± 0.25 mm, 35.8± 0.58 mm, 34.7± 0.51 mm and 32.7±0.25 mm was obtained by Plectranthus arabicus against Klebsiella ...
Source: Saudi Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 8 December 2017 Source:Respiratory Medicine Case Reports Author(s): Tomohiro Sakamoto, Akira Yamasaki, Yoshihiro Funaki, Tomoya Harada, Ryota Okazaki, Yasuyuki Hasegawa, Yuriko Sueda, Takehito Fukushima, Masahito Morita, Akihiro Yamamoto, Masahiro Kodani, Eiji Shimizu A 62-year old man was admitted to our hospital with a 2-week complaint of a dry cough, general fatigue, and dyspnea on effort. He has been an onion farmer for several years and developed these symptoms after cleaning up onion peels with air compressors. A chest roentgenogram and computed tomography showed a ground glass sha...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
The incidence of infection with Aspergillus has increased in recent years. A. fumigatus of genus Aspergillus is responsible for more than 90% of invasive disease while flavus, terreus, and niger are responsible for the majority of remaining invasive aspergillosis cases. Metabolites (toxins and enzymes) make this eukaryotic group successful for the survival in a host thereby interacting and overcoming the host immune system. A total of 80 filamentous fungi (Aspergillus flavus (20 isolates), A. fumigatus (15), A. niger (30) and A. terreus (15) isolated from suspected patients (suffering from severe persisting asthma, COPD an...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Clinical Problems Asthma Source Type: research
Discussion: ABPA as an occupational disease and a particular risk in waste management have not yet been described. In both cases, the misdiagnosis of drug-resistant pneumonia was initially made. The necessary change of workplace was thus delayed. Exposure to moulds, however, was not entirely avoidable at either of the new workplaces. Infiltrates and type I typical airway obstruction developed again. ABPA is a work-related serious illness which requires a strict avoidance of allergen exposition and thus a change of workplace or even occupation.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Occupational and Environmental Health Source Type: research
Conclusions: Frequency of infection in APAP cases were similar to the previous report. Infection might improve or deteriorate the clinical course of APAP.Financial support: This study was partially granted from AMED; DLD/14526278 to Y. Inoue and T. Arai and PAP/14526182 to Y. Inoue.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Diffuse Parenchymal Lung Disease Source Type: research
Conclusion: Incidence of infectious diseases was relatively high in patients with nivolumab treatment. ICI has a potential risk for infectious disease regardless of steroid use.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Lung Cancer Source Type: research
Introduction: Hospital re-admissions after lung transplant (LT) negatively affect quality of life, and costs. Reports on ICU readmission (ICU-r) have been limited to short series.Methods: Prospective, multicenter, observational study including 174 consecutive LT adults requiring ICU readmission (august 2012-16). We evaluated epidemiological features of this population and studied the outcomes. T student was used for statistical comparisons.Results: Overall, 118 (68.2%) ICU-r were due to acute respiratory failure (ARF) and 78 (44.8%) had an infectious cause, with pneumonia the most prevalent (73%). Acute cellular and humora...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Transplantation Source Type: research
• Co-infection is frequent in influenza-related ARDS requiring ECMO support• Staphylococcus aureus is the most common pathogen• Panton–Valentin leukocidin-producing Staphylococcus aureus is frequent• Aspergillus fumigatus co-infection is frequent in influenza-associated severe pneumonia
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Source Type: research
Publication date: Available online 10 November 2017 Source:Saudi Pharmaceutical Journal Author(s): Nouf M. Al-Enazi, Amani S. Awaad, Mohamed E. Zain, Saleh I. Alqasoumi The antimicrobial, antioxidant, and anticancer activities of ethanolic extract of Laurencia catarinensis, L. majuscula and Padina pavonica were determined. The highest antibacterial activity; 23.40 ± 0.58 mm (00.98 µg/ml) and 22.60 ± 2.10 mm (03.90 µg/ml) were obtained against Klebsiella pneumonia by Laurencia catarinensis and Padina pavonica, respectively. However, Padina pavonica showed excellent antibacterial ac...
Source: Saudi Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
We report the case of a 53‐year‐old male with a history of acute myelogenous leukemia, who suffered the rupturing of a right‐sided pulmonary artery pseudoaneurysm combined with pneumonia. He underwent a right‐sided lower lobectomy. The resected lung tissue demonstrated a mycotic pseudoaneurysm of a pulmonary artery branch together with a filamentous fungal infection. Pseudoaneurysms are caused by the breaching of all layers of a blood vessel wall. The extravasated blood is trapped by the surrounding extravascular tissue or clots. Cladosporium was detected during a polymerase chain reaction‐based analysis followed...
Source: Pathology International - Category: Pathology Authors: Tags: Case Report Source Type: research
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