Evaluation of CPP-ACP and Fluoride on Inhibition of Human Enamel demineralisation: Cross-sectional Hardness and MicroCT Studies

Miyahira, Karla / Coutinho, Thereza / Silva, Eduardo / Pereira, Andr é / Tostes, MonicaPage 549 - 555Purpose: To evaluate the in vitro effect of different application frequencies of dentifrices containing CPP-ACP and fluoride on enamel demineralisation inhibition using a pH cycling model.Materials and Methods: One hundred twenty blocks of human enamel were divided into 8 groups according to the treatment and number of times that the dentifrice slurry was applied (3 or 5 times). Control: dentifrice without fluoride (CO3 and CO5); fluoride dentifrice (FD3 and FD5, commercial dentifrice 1100 ppm as NaF); MI Paste (MP3 and MP5, Recaldent) and MI Paste Plus (MPP3 and MPP5, Recaldent 900 ppm as NaF). After pH cycling, cross-sectional microhardness (CSH) measurements were taken. The demineralised enamel changes were analyzed on three blocks per group by MicroCT. Data were analyzed by ANOVA and Tukey's HSD post-hoc test (p = 0.05).Results: Statistically significantly higher CSH values (p
Source: Oral health and Preventive dentistry - Category: Dentistry Source Type: research