Frequency of Desaturation and Association With Hemodynamic Adverse Events During Tracheal Intubations in PICUs
Objectives: Oxygen desaturation during tracheal intubation is known to be associated with adverse ICU outcomes in critically ill children. We aimed to determine the occurrence and severity of desaturation during tracheal intubations and the association with adverse hemodynamic tracheal intubation–associated events. Design: Retrospective cohort study as a part of the National Emergency Airway Registry for Children Network’s quality improvement project from January 2012 to December 2014. Setting: International PICUs. Patients: Critically ill children younger than 18 years undergoing primary tracheal intubations in the ICUs. Interventions: tracheal intubation processes of care and outcomes were prospectively collected using standardized operational definitions. We defined moderate desaturation as oxygen saturation less than 80% and severe desaturation as oxygen saturation less than 70% during tracheal intubation procedures in children with initial oxygen saturation greater than 90% after preoxygenation. Adverse hemodynamic tracheal intubation–associated event was defined as cardiac arrests, hypo or hypertension requiring intervention, and dysrhythmia. Measurements and Main Results: A total of 5,498 primary tracheal intubations from 31 ICUs were reported. Moderate desaturation was observed in 19.3% associated with adverse hemodynamic tracheal intubation–associated events (9.8% among children with moderate desaturation vs 4.4% without desat...
CONCLUSIONS: The similar prevalence of psoriasis-related morbidities in MRS and in psoriasis may further support an association between MRS and psoriasis. PMID: 29781258 [PubMed - as supplied by publisher]
HIGH blood pressure symptoms include chest pain, headaches and difficulty breathing. You could lower your risk of hypertension by adding this cheap, refreshing vegetable to your diet, it ’s been revealed.
This study reports the effect of disease-modifying therapies for rheumatoid arthritis (RA) on systolic and diastolic blood pressure (SBP, DBP) over 6 months and incident hypertension over 3 years in a large administrative database. Methods We used administrative Veterans Affairs databases to define unique dispensing episodes of methotrexate, leflunomide, sulfasalazine, hydroxychloroquine, tumor necrosis factor inhibitors, and prednisone among patients with RA. Changes in SBP and DBP in the 6 months before disease-modifying antirheumatic drug initiation were compared with changes observed in the 6 months after initiation...
Conclusions Regardless of BP magnitude, most RA clinic visits lacked documented communication about BP despite compounded CVD risk. Future work should study how rheumatology clinics can facilitate follow-up of high BPs to address HTN as the most common and reversible CVD risk factor.
Pulse pressure amplification and cardiac autonomic dysfunction in patients with type 2 diabetes mellitus, Published online: 23 May 2018; doi:10.1038/s41371-018-0070-1Pulse pressure amplification and cardiac autonomic dysfunction in patients with type 2 diabetes mellitus
Health-promoting behaviors and quality of life in older adults with hypertension as compared to a community control group, Published online: 23 May 2018; doi:10.1038/s41371-018-0073-yHealth-promoting behaviors and quality of life in older adults with hypertension as compared to a community control group
Performance of NoSAS score versus Berlin questionnaire for screening obstructive sleep apnoea in patients with resistant hypertension, Published online: 23 May 2018; doi:10.1038/s41371-018-0072-zPerformance of NoSAS score versus Berlin questionnaire for screening obstructive sleep apnoea in patients with resistant hypertension
CONCLUSION: The data contradicted national studies reporting primary hypertension as the main cause of chronic kidney disease (CKD). A high rate of unknown causes and categorization bias were observed mainly in relation to primary hypertension as a cause of CKD, which affects the overall prevalence of causes of ESRD in patients on dialysis. PMID: 29782632 [PubMed - as supplied by publisher]
In this study, we discuss dialysis in the final phase of life and present a systematic way to address this dilemma. PMID: 29782631 [PubMed - as supplied by publisher]
CONCLUSION: The prevalence of IgAN was lower in Salvador than other regions of Brazil. Chronic histological lesions and laboratory markers of severe disease were frequent. M1 and T2 MEST-C scores were correlated with markers of renal dysfunction. PMID: 29782630 [PubMed - as supplied by publisher]