Molecular Adjuvants Based On Plasmids Encoding Protein Aggregation Domains Affect Bone Marrow Niche Homeostasis.

CONCLUSION: The above findings provide compelling support to the thesis that adjuvants based on plasmids encoding protein aggregation domains disrupt the physiological features of the bone marrow elements.
PMID: 29303078 [PubMed - as supplied by publisher]

Source: Current Gene Therapy - January 5, 2018 Category: Genetics & Stem Cells Authors: Sabbieti MG, Lacava G, Amaroli A, Marchetti L, Censi R, Di Martino P, Agas D Tags: Curr Gene Ther Source Type: research