Aptamers and aptasensors as novel approach for microbial detection and identification: An appraisal.

Aptamers and aptasensors as novel approach for microbial detection and identification: An appraisal. Curr Drug Targets. 2018 Jan 04;: Authors: Jamil B, Syed MA Abstract Tremendous efforts through dedicated research have been made for the development of robust, point of care, portable, cost effective, sensitive and specific assays of microbial detection for a wide range of applications. Biosensing and nanotechnology offer novel strategies of designing state of the art devices and assay formats with enhanced sensitivity and all other desired features. Monoclonal antibodies have been in use as biorecognition elements for decades. However, recent studies have demonstrated superiority of aptamers to monoclonal antibodies in a number of applications. Many of the research groups have successfully utilized aptamers as capture probes in developing biosensors for microbial detection. A biosensor utilizing aptamer as a recognition probe for specific detection of targets such as microbes or their products is called an aptasensor. In the present article, authors present an overview of the recent advances made in the field of aptamers and aptasensor for the detection and identification of microbial agents. PMID: 29303077 [PubMed - as supplied by publisher]
Source: Current Drug Targets - Category: Drugs & Pharmacology Authors: Tags: Curr Drug Targets Source Type: research