The role of oxytocin receptor gene (OXTR) and mother's emotional warmth in predicting adulthood sociability

This study used data from 2289 (55% female) participants from the ongoing prospective Young Finns Study. Maternal emotional warmth was assessed in 1980 when the participants were 3–18years old. Participants' sociability temperament was measured at five follow-ups, from 1992 to 2012. Emotional warmth in childhood and OXTR genotype were not directly associated with temperamental sociability. We found a nominally significant gene–environment interaction (p =.03) suggesting that participants with a genetic profile of rs1042778 T-allele and rs2254298 A-allele are affected high versus low emotional warmth, whereas homozygotes of both G-alleles are unaffected by the same environmental influence. Our findings should be, however, interpreted as a null result as the interaction effect did not survive correction for multiple testing.
Source: Personality and Individual Differences - Category: Psychiatry & Psychology Source Type: research