P2X7 receptor mediates NLRP3-dependent IL-1 β secretion and parasite proliferation in Toxoplasma gondii-infected human small intestinal epithelial cells

Toxoplasma gondii can invade and replicate in all nucleated cells in a wide range of host species, and infection induces IL-1 β production. IL-1β plays central roles in the stimulation of the ...

Source: Parasites and Vectors - January 2, 2018 Category: Microbiology Authors: Juan-Hua Quan, Rui Huang, Zhuang Wang, Shuai Huang, In-Wook Choi, Yu Zhou, Young-Ha Lee and Jia-Qi Chu Tags: Research Source Type: research