Isolation and complete genome sequencing of Zika virus imported from the Dominican Republic to Japan.

Isolation and complete genome sequencing of Zika virus imported from the Dominican Republic to Japan.
Jpn J Infect Dis. 2017 Dec 26;:
Authors: Ozawa H, Tajima S, Nakayama E, Kato K, Yamashita A, Sekizuka T, Kuroda M, Usuku S
Abstract
  Zika virus (ZIKV) infection has been documented within Central and South America, Asia, and Africa. Here we report the isolation of virus from a patient infected with ZIKV returning to Japan from the Dominican Republic. The ZIKV strain was imaged by electron microscopy and its complete genome sequence was analyzed. Phylogenetic analysis and molecular characterization revealed that the strain was of the Asian lineage, and carried two unique mutations in its NS5 region. These mutations are characteristic of strains that originated in the Dominican Republic and the USA in 2016.
PMID: 29279447 [PubMed - as supplied by publisher]

Source: Japanese Journal of Infectious Diseases - December 26, 2017 Category: Infectious Diseases Authors: Ozawa H, Tajima S, Nakayama E, Kato K, Yamashita A, Sekizuka T, Kuroda M, Usuku S Tags: Jpn J Infect Dis Source Type: research