CD4+ T Cells are Exhausted and Show Functional Defects in Chronic Lymphocytic Leukemia.

CONCLUSION: Given that the exhaustion phase of T cells can be reversible, targeted blocking of immune inhibitory molecules could be a promising tool to restore the host immune responses against leukemic cells in CLL. PMID: 29276179 [PubMed - in process]
Source: Iranian Journal of Immunology - Category: Allergy & Immunology Tags: Iran J Immunol Source Type: research