Mid ‐ to long‐term results of total ankle replacement in patients with haemophilic arthropathy: A 10‐year follow‐up
ConclusionTotal ankle replacement in the presence of advanced haemophilic arthropathy is a viable treatment option with favourable mid‐/long‐term results, maintaining mobility of the ankle joint.
Conclusions: Valoctocogene roxaparvovec was found to be cost-saving-on average by about $6.8 million per patient-and more effective than prophylactic therapy for treatment of hemophilia A. The comparative benefit of gene therapy was observed across a broad range of simulated patients that were representative of the real-world severe hemophilia A population. PMID: 31971453 [PubMed - as supplied by publisher]
Title: Gene Therapy May Be Long-Term Cure for Type of HemophiliaCategory: Health NewsCreated: 1/2/2020 12:00:00 AMLast Editorial Review: 1/3/2020 12:00:00 AM
CONCLUSION: Whereas People With Advanced Hemophilic Arthropathy Of The Ankle Are Prone To Ameliorate Pain And Range Of Motion Following Tar, There Is Deficient Knowledge To Regularly Recommend Its Use. Adverse Events And Infection Percentages Are Disturbing. Moreover, The Lack Of Survival Analysis Knowledge Makes It Difficult To Assess The Benefit To People With Hemophilia. Tar Is A Demanding Surgical Procedure And Its Survival Is Not Comparable To That After Hip Or Knee Arthroplasty. PMID: 31820705 [PubMed - as supplied by publisher]
Abstract Haemophilia is a blood clotting disorder known as 'Christmas disease' caused when the blood has defect with the clotting factor(s). Bleeding leads various issues, such as chronic pain, arthritis and a serious complication during the surgery. Identifying this disease is mandatory to take the necessary treatment and maintains the normal clotting. It has been proved that the level of factor IX (FIX) is lesser with haemophilia patient and the attempt here is focused to quantify FIX level by interdigitated electrode (IDE) sensor. Single-walled carbon nanotube (SWCNT) was utilized to modify IDE sensing surface....
A 32-year-old man, with a history of severe hemophilia A, presented with a history of right-sided abdominal pain for 1 week. He was not on any prophylactic factor VIII. On physical examination, he had a distended abdomen with guarding and tenderness on the right side of the abdomen. There was no organomegaly. On percussion, the patient had a dull note on the right flank and resonant note on the left side. There wa s no shifting dullness. Laboratory investigations revealed low hemoglobin (6.8 gm/dL) and isolated activated partial thromboplastin time prolongation (control 33 s, test 96 s).
This study was designed to investigate the effects of pulsed Nd:YAG laser on pain, postural stability, and weight-bearing pattern in children with hemophilic ankle arthropathy. Forty children diagnosed with hemophilia type A (age, 8 –16 years) were randomly allocated to either the treatment group (n = 20) who received a three-phase active therapy with pulsed Nd:YAG laser thrice/week (total energy was 1500 J) plus a physical exercise program for four consecutive weeks, or the placebo group (n = 20) who received placebo laser plus the physical exercise program. Pain, postural control (i.e., directional control [DC], en...
We present a case of a 68-year-old Hispanic female with a history of factor VII deficiency who presented with shortness of breath, chest pain, and palpitations and was found to have pulmonary embolism. Our patient did not have any of the above-mentioned thrombotic risk factors. Our case and review of the literature show that factor VII deficiency does not provide protection against thrombosis. PMID: 31590173 [PubMed - as supplied by publisher]
We report a young child who had a minor injury and calf swelling. He was initially diagnosed with deep vein thrombosis (DVT). Magnetic resonance imaging confirmed intramuscular hematoma and factor VIII assay confirmed hemophilia.
Published on 2019-07-24 12:39:28