Analogues of Modafinil for treating sleep and attention disorders

The National Institute on Drug Abuse ’s Medicinal Chemistry Section seeks partners interested in collaborative research to co-develop analogues of modafinil for the treatment of drug abuse and sleep and attention disorders.IC: NIDANIH Ref. No.: E-073-2013Advantages: Higher affinity for monoamine transporters (DAT, SERT, and NET) compared to modafinilAnalogues have lower effective dosesBetter bioavailability than modafinilImproved water solubility over modafinilApplications: Therapeutic agent for substance abuse (such as nicotine, cocaine, methamphetamine, opioids), for attention/cognitive disorders (such as ADHD), and for sleep disorders.Development Status: Discovery (Lead Identification)Updated On: Dec 20, 2017Provider Classifications: Publications: Patent Application: 14/772,486Patent Authority: U.S.Licensing Contacts: Lead Inventor: Inventor IC: NIDAInventor Lab URL: https://irp.nih.gov/pi/amy-newmanInv Is lead: LPM Phone: [phone]LPM Email: [e-mail] Classification: TherapeuticsDTDT Description: TherapeuticsPat Filing Date: 2015-09-03T00:00:00Collaboration Sought: YesInstitute or Center: NIDACollaboration Opportunity: Licensing onlyRelated Invention: E-251-2002E-128-2006Inventor First Name: AmyInventor Last Name: Newman

Source: NIH OTT Licensing Opportunities - December 21, 2017 Category: Research Authors: ajoyprabhu3 Source Type: research