Type I IFN –related NETosis in ataxia telangiectasia and Artemis deficiency

Pathological inflammatory syndromes of unknown etiology are commonly observed in ataxia telangiectasia (AT) and Artemis deficiency. Similar inflammatory manifestations also exist in patients with STING-associated vasculopathy in infancy (SAVI).

Source: Journal of Allergy and Clinical Immunology - November 15, 2017 Category: Allergy & Immunology Authors: Ersin Gul, Esra Hazar Sayar, Bilgi Gungor, Fehime Kara Eroglu, Naz Surucu, Sevgi Keles, Sukru Nail Guner, Siddika Findik, Esin Alpdundar, Ihsan Cihan Ayanoglu, Basak Kayaoglu, Busra Nur Geckin, Hatice Asena Sanli, Tamer Kahraman, Cengiz Yakicier, Meltem M Source Type: research