Associations between infant fungal and bacterial dysbiosis and childhood atopic wheeze in a nonindustrialized setting

Asthma is the most prevalent chronic disease of childhood. Recently, we identified a critical window early in the life of both mice and Canadian infants during which gut microbial changes (dysbiosis) affect asthma development. Given geographic differences in human gut microbiota worldwide, we studied the effects of gut microbial dysbiosis on atopic wheeze in a population living in a distinct developing world environment.

Source: Journal of Allergy and Clinical Immunology - December 11, 2017 Category: Allergy & Immunology Authors: Marie-Claire Arrieta, Andrea Ar évalo, Leah Stiemsma, Pedro Dimitriu, Martha E. Chico, Sofia Loor, Maritza Vaca, Rozlyn C.T. Boutin, Evan Morien, Mingliang Jin, Stuart E. Turvey, Jens Walter, Laura Wegener Parfrey, Philip J. Cooper, Brett Finlay Source Type: research