In Reply

We appreciate Dr. Xueet al.’s interest in our paper. Several points are made that require clarification. First, the notion that occurrence and severity as well as duration of acute kidney injury (AKI) in the early postoperative period after cardiac surgery is responsible for major adverse kidney events has been called into question by studies that demonstrated that only part of the risk for major adverse kidney events comes from an early AKI in the postoperative period.1 These patients are also at risk for late AKI and progression of underlying chronic kidney disease and risk for death unrelated to AKI.
Source: Anesthesiology - Category: Anesthesiology Source Type: research