Impact of different antiretroviral strategies on total HIV-DNA level in virologically suppressed HIV-1 infected patients.

Conclusion The data emphasize that HIV-DNA level represents a predictive factor in long-term suppressive therapy patients. In addition, the diminished reservoir, only observed in patients treated with the NRTI-sparing regimen RAL plus PI/r before immunological and virological derangement, suggest that latest generation drugs, such as integrase inhibitors, might represent an optimal chance in the management of HIV infection. PMID: 29210661 [PubMed - as supplied by publisher]
Source: Current HIV Research - Category: Infectious Diseases Authors: Tags: Curr HIV Res Source Type: research