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Transpedal Access for the Management of Complex Peripheral Artery Disease.

CONCLUSION: Based on the results of this systematic review, transpedal access appears to be a safe and effective technique for complex PAD. PMID: 29207364 [PubMed - in process]
Source: The Journal of Invasive Cardiology - Category: Cardiology Tags: J Invasive Cardiol Source Type: research

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Source: Circulation: Cardiovascular Quality and Outcomes - Category: Cardiology Authors: Tags: Health Services Data Report Source Type: research
The prevalence and debilitating nature of peripheral artery disease (PAD) mandate the development and aggressive implementation of the most efficacious treatment strategies available. Research has clearly demonstrated that supervised exercise in individuals with PAD and lifestyle-limiting claudication leads to improved outcomes in the short term. An important factor in determining the relative value of exercise training in PAD rehabilitation is the extent to which the benefits are sustained over time.
Source: Journal of Vascular Nursing - Category: Nursing Authors: Source Type: research
ard R Abstract OBJECTIVE/BACKGROUND: Heparin coating has recently been shown to reduce the risk of graft failure in arterial revascularisation, at least transiently. The aim of this study was to assess the cost-effectiveness of heparin coated versus standard polytetrafluoroethylene grafts for bypass surgery in peripheral artery disease from a long-term healthcare system perspective. METHODS: Cost-effectiveness evaluation was conducted alongside the Danish part of the Scandinavian Propaten trial in which 431 patients planned for femoro-femoral or femoro-popliteal bypass surgery were randomised to either type o...
Source: PubMed: Eur J Vasc Endovasc ... - Category: Surgery Authors: Tags: Eur J Vasc Endovasc Surg Source Type: research
Abstract Current management of peripheral arterial disease involves risk factor modification and revascularisation, but many patients are still left with debilitating symptoms. Therefore, new treatment strategies are needed. The importance of nitric oxide, and its role in regulating endothelial function, is well-established. Altering the nitric oxide pathway has been extensively studied as a means of treating vascular disease, including peripheral arterial disease. Statins and ACE inhibitors have been shown to enhance endogenous nitric oxide and improve intermittent claudication symptoms. Studies using l-arginine ...
Source: Current Opinion in Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Curr Opin Pharmacol Source Type: research
CONCLUSIONS: Treadmill training in PAD patients through UPR and Nrf2 up-regulation may trigger hypoxic adaptation similar to conditioning, thus modifying cell survival. PMID: 29540636 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
Peripheral Artery Disease (PAD) patients with disabling claudication (Rutherford III or worse) are often treated medically or surgically to improve their functional activity. However, we do not typically measure objective, patient reported, measures of functional activity. More commonly, we measure Ankle Brachial Indices (ABIs), obtain imaging studies and rely on the subjective recall of a patient ’s symptoms. This is true during our initial evaluation as well as post intervention- Are we measuring the right metrics? We believe there is value in investigating ways to track a patient’s activity in the real world...
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: Abstracts Accepted for Presentation During the 42nd Annual Meeting of the Vascular and Endovascular Surgery Society Source Type: research
Cardiovascular Systems (NSDQ:CSII) today released 18-month results from the Liberty 360° study of peripheral artery disease interventions, touting high freedom from adverse events and amputations. Results from the study were presented by Dr. William Gray of Wynnewood, Penn.’s Lankenau Heart Institute at the Cardiovascular Research Technologies 2018 interventional cardiology conference in Washington D.C., the St. Paul, Minn.-based company said. “The 18-month Liberty 360° results continue to show that PVI, including the use of orbital atherectomy, can lead to amputation free survival for patients wit...
Source: Mass Device - Category: Medical Devices Authors: Tags: Clinical Trials Vascular Cardiovascular Systems Inc. Source Type: news
The most common clinical presentation of peripheral artery disease (PAD) comprises intermittent claudication but about one third of patients will progress to critical limb ischemia (CLI) characterized by rest pain and/or tissue loss, which is the most severe limb manifestation of PAD. Paclitaxel-coated balloons are safe and effective in treating PAD. This ongoing multicenter registry study is designed to assess the safety and effectiveness of the Lutonix ® 014 Drug Coated PTA Dilatation Catheter (DCB) for the treatment of stenosis or occlusion of native below-the-knee (BTK) arteries in a real world clinical practice.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 16: Vascular Therapy 1 Source Type: research
Conclusion In a real-world environment, the BIOLUX P-III registry preliminary results confirm the safety and efficacy of the Paclitaxel-Coated Passeo-18 Lux balloon as a stand-alone treatment option for atherosclerotic infrainguinal arteries.Resumo Contexto O manejo endovascular de art érias infrainguinais ateroscleróticas recentemente tem mudado para dispositivos farmacológicos, desenhados para impedir localmente o processo de reestenose. Numerosos estudos clínicos descrevem uma vantagem da angioplastia com uso de balões farmacológicos sobre os balões convencionais no trat ...
Source: Jornal Vascular Brasileiro - Category: Surgery Source Type: research
Conclusions: PORTRAIT systematically collected serial PAD-specific health status data as a foundation for risk stratification, comparative effectiveness studies, and clinicians’ adherence to quality-based performance measures. Clinical Trial Registration: URL: https://www.clinicaltrials.gov. Unique identifier: NCT01419080.
Source: Circulation: Cardiovascular Quality and Outcomes - Category: Cardiology Authors: Tags: Quality and Outcomes, Peripheral Vascular Disease, Vascular Disease Methods Paper Source Type: research
More News: Angiography | Cardiology | Cardiovascular | Heart | Intermittent Claudication | Peripheral Vascular Disease (PVD) | Study | Ultrasound