Role of tumor necrosis factor- α in epithelial-to-mesenchymal transition in transplanted kidney cells in recipients with chronic allograft dysfunction.

CONCLUSIONS: TNF-α induced EMT via the TNF-α/Akt/Smurf2 signaling pathways, and it may play a role in aggravating allograft kidney interstitial fibrosis in CAD patients.
PMID: 29174387 [PubMed - as supplied by publisher]

Source: Gene - November 23, 2017 Category: Genetics & Stem Cells Authors: Zhao C, Xu Z, Wang Z, Suo C, Tao J, Han Z, Gu M, Tan R Tags: Gene Source Type: research