The evaluation of cellular immune function in elderly patients with systemic lupus erythematosus.
Conclusions: The significantly lower CD4+ /CD8+ ratio among SLE patients over 60 years old is associated with deregulated immune responses and the development of SLE. A low ANA titer (1:160) is common in healthy elders, emphasizing the importance of considering age when determining if the evaluation of ANA titers is to be included in autoimmune disease diagnosis.
PMID: 29172398 [PubMed - as supplied by publisher]
Source: The Korean Journal of Internal Medicine - Category: Internal Medicine Authors: Men K, Chen Y, Zhang J, Wei D Tags: Korean J Intern Med Source Type: research