Cancer immunotherapy: Rewiring cancer cells
Nature Reviews Drug Discovery 16, 828 (2017).
doi:10.1038/nrd.2017.242
Author: Anna Dart
A number of factors ranging from the scarcity of tumour-specific neoantigens, tumour immunosuppression and toxicity caused by systemic delivery of immunomodulators restrict the efficiency of cancer immunotherapies. To overcome these obstacles, Nissim, Wu et al. have engineered a synthetic gene circuit enabling the production
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Anna Dart Tags: Research Highlight Source Type: research
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