Self-Resolving sp. Colonization in a Lung Transplant Patient

Cladophialophora spp. are dematiaceous moulds that are responsible for causing a variety of human infections in both immunocompetent and immunocompromised individuals. Infections caused by Cladophialophora spp. most commonly involve the skin and soft tissue and the central nervous system (CNS). Cladophialophora sp. infections involving the skin and soft tissues are often referred to as chromoblastomycosis, a slowly developing condition that rarely disseminates and can be treated with surgical excision and/or antifungal chemotherapy.
Source: Clinical Microbiology Newsletter - Category: Microbiology Authors: Tags: Case Report Source Type: news

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Conclusions: The neutrophilic infiltration had an important role in the containment of infection to prevent fungal spreading, including in immunodeficient mice. The fungal elimination was dependent on T lymphocytes. The re-exposure of C57BL/6 mice to Fonsecaea pedrosoi caused a delay in resolving the infection, and appearance of muriform cells, which may indicate that re-exposure to fungi, might lead to chronicity of infection.
Source: Anais Brasileiros de Dermatologia - Category: Dermatology Source Type: research
Publication date: March 2019Source: Journal of Global Antimicrobial Resistance, Volume 16Author(s): Alessandra Helena da Silva Hellwig, Daiane Heidrich, Régis Adriel Zanette, Maria Lúcia ScrofernekerAbstractChromoblastomycosis (CBM) is a chronic granulomatous mycosis caused by dematiaceous fungi that affects cutaneous and subcutaneous tissues. The standard antifungal drug for treatment is itraconazole, followed by terbinafine. However, cure rates vary from 15% to 80% when these drugs are used as monotherapy. A systematic review of the in vitro susceptibility of CBM agents to antifungal drugs, alone and in com...
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Conclusion: Chromoblastomycosis was the most common subcutaneous mycoses seen in northeast India followed by sporotrichosis. The diagnosis remained a challenge in a few cases as the culture positivity was very low. Suppurative granulomas in histopathology played a corroborative role. Therapeutic trial of itraconazole for 2 months was worth trying in such cases.
Source: Indian Journal of Dermatology - Category: Dermatology Authors: Source Type: research
We report a woman who was treated before with mycological cure, but she experience a relapse requiring treatment again. Direct microscopic examination and skin biopsy with culture were necessary to identify a Exophiala psychrophila, and for our knowledge this is the first case reported.
Source: Medical Mycology Case Reports - Category: Biology Source Type: research
Gheniffer Fornari, Renata Rodrigues Gomes, Juliana Degenhardt-Goldbach, Suelen Silvana dos Santos, Sandro Rog ério de Almeida, Germana Davila dos Santos, Marisol Dominguez Muro, Cleusa Bona, Rosana Herminia Scola, Edvaldo S. Trindade, Israel Henrique Bini, Lisandra Santos Ferreira-Maba, Daiane Rigoni Kestring, Mariana Machado Fidelis do Nascimento, Bruna Jacomel Favoreto de Souza Lima, Morgana F. Voidalesk i, Douglas André Steinmacher, Bruna da Silva Soley, Shuwen Deng, Anamelia Lorenzetti Bocca, Moises B. da Silva, Claudio G. Salgado, Conceição Maria Pedroso e Silva de Azevedo, Vania Aparecida ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Publication date: Available online 25 September 2018Source: Journal of Global Antimicrobial ResistanceAuthor(s): Alessandra Helena da Silva Hellwig, Daiane Heidrich, Régis Adriel Zanette, Maria Lúcia ScrofernekerAbstractChromoblastomycosis (CBM) is a chronic granulomatous mycosis caused by dematiaceous fungi, which affects cutaneous and subcutaneous tissues. The standard antifungal drug for treatment is itraconazole, followed by terbinafine. However, the cure rates vary from 15 to 80% when these drugs are used in monotherapy. A systematic review on the in vitro susceptibility of CBM agents to antifungal drugs...
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Clinical and Experimental Dermatology, EarlyView.
Source: Clinical And Experimental Dermatology - Category: Dermatology Authors: Source Type: research
Authors: Sideris ER, Ge L PMID: 30257629 [PubMed - in process]
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
We report the identification of four different fungal causative agents of chromoblastomycosis by reverse line blotting hybridization (RLB) based on biotin-labeled PCR products and amine labeled probes to hybridize. Sixty five reference strains, including type strains, i.e. Fonsecaea pedrosoi, F. monophora, F. nubica, and Phialophora verrucosa, obtained from the CBS-KNAW were included in this study.Internal transcribed spacer 1 (ITS1) regions of relevant species were aligned and adjusted using BIONUMERICS v. 4.61 in order to design four specific probes to identify informative nucleotide polymorphisms. The final identificati...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Journal of the European Academy of Dermatology and Venereology,Volume 0, Issue ja, -Not available-.
Source: Journal of the European Academy of Dermatology and Venereology - Category: Dermatology Authors: Source Type: research
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