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Changes in gray and white matter in subgroups within the tinnitus population.

In this study, we investigated gray and white matter changes in subgroups within the larger tinnitus population related to differences in severity or duration of tinnitus symptoms. Tinnitus is the illusory perception of sound in the absence of an external source, most often experienced as a chronic condition. The psychological reaction to the sound constitutes the severity, or degree of discomfort experienced, and the duration refers to the time since onset of chronic tinnitus. We used voxel- and surface-based morphometry to investigate gray matter changes and diffusion tensor imaging (using fractional anisotropy, or FA, metrics) to assess changes in orientation of white matter tracts, using both whole brain and region of interest analyses. Whole brain analyses revealed decreased cortical thickness in the left parahippocampal gyrus in those with more severe tinnitus compared to a group with a milder reaction, and reduced gray matter volume in left anterior cingulate in those with mild tinnitus compared to a normal hearing control group without tinnitus. In the analysis based on FA, no significant differences were revealed between the subgroups or with respect to control groups in either whole brain or region of interest analyses. Our results suggest that these subgroups within the tinnitus population likely exhibit different anatomical alterations related to the disorder, which may explain the variable findings in the literature, particularly in terms of gray matter. PMI...
Source: Brain Research - Category: Neurology Authors: Tags: Brain Res Source Type: research

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(Reuters Health) - A sound-emitting device worn in the ear during sleep may train the brain to ignore an annoying chronic ringing in the ears, a new study suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Sensory systems: Bimodal cochlear nucleus stimulation alleviates tinnitus, Published online: 19 January 2018; doi:10.1038/nrneurol.2018.1Sensory systems: Bimodal cochlear nucleus stimulation alleviates tinnitus
Source: Nature Reviews Neurology - Category: Neurology Authors: Source Type: research
Conclusion We conclude that stapes surgery is effective for the treatment of tinnitus (average improvement is 85.52%), and hearing loss (average improvement is 93%). When deciding about the surgical indication in patients with otosclerosis, the presence and level tinnitus should be considered as well as the level of hearing.
Source: Brazilian Journal of Otorhinolaryngology - Category: ENT & OMF Source Type: research
(Wyss Center for Bio and Neuroengineering) The Wyss Center, a non-profit neurotechnology translation organization, has signed a partnership agreement with German medical engineering company, CorTec. The partners will work together on research, design and development of a device for continuous, long-term, monitoring of the brain's electrophysiological signals for clinical diagnostic and therapeutic applications. The planned device will sit on the skull, beneath the skin and has potential uses in epilepsy monitoring, tinnitus regulation through neurofeedback, neuromodulation for dyslexia and other brain circuit disorders.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Objective: To assess the prevalence of hearing loss and factors affecting hearing care use among Asian Americans, using the first nationally representative sample of Asian Americans. Study Design: National cross-sectional survey. Setting: Ambulatory examination centers. Patients: Three thousand six hundred twelve adults (522 Asian American) aged 20 to 69 in the 2011 to 2012 National Health and Examination Survey with pure-tone audiometry. Main Outcome Measure(s): Percentage with hearing loss, undertaking a hearing test before the study, and hearing aid use. Hearing loss was defined as better hearing ear speec...
Source: Otology and Neurotology - Category: ENT & OMF Tags: Sensorineural Hearing Loss and Tinnitus Source Type: research
Conclusion: The ELH was progressive in the long-term course of the disease in this large population of definite MD patients, but short-term and middle-term fluctuations of the symptom severity did not involve measurable variations of the ELH. Furthermore, the symptom severity did not decrease with increasing disease duration.
Source: Otology and Neurotology - Category: ENT & OMF Tags: Vestibular Disorders Source Type: research
This study aimed to evaluate patients with tinnitus in terms of mean platelet volume and platelet distribution width, and to explore neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio, recently reported in the literature as being possible inflammation markers. METHODS: This study comprised 64 tinnitus patients and 64 age-matched healthy controls. Statistical significance level was accepted as p
Source: Journal of Laryngology and Otology - Category: ENT & OMF Tags: J Laryngol Otol Source Type: research
An intervention combining calibrated auditory and electrical pulse stimulation shows preliminary but intriguing potential to treat this often debilitating condition.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
Strategies for a regenerative therapy of hearing loss. HNO. 2018 Jan 09;: Authors: Diensthuber M, Stöver T Abstract Despite impressive technical progress in the field of conventional hearing aids and implantable hearing systems, the hopes for the treatment of inner ear diseases such as hearing loss and tinnitus have become increasingly directed toward regenerative therapeutic approaches. This review discusses the currently most promising strategies for hair cell regeneration in the inner ear to treat hearing loss, including stem cell-based, gene transfer-based, and pharmacological interventio...
Source: HNO - Category: ENT & OMF Tags: HNO Source Type: research
BOSTON (CBS) – It is estimated that 1 in 5 people suffer from tinnitus, a ringing or buzzing in the ear, that can be so intrusive it can affect a person’s quality of life. Now researchers at the University of Michigan say a new experimental device that targets unruly nerve cells in the brain can help quiet the “phantom sounds” of tinnitus. Human study participants who used the device daily said the loudness of the sounds was reduced and their quality of life improved. Some people have tinnitus so bad they can’t do their jobs and can’t function at home, and current treatments include usin...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health Healthwatch Local News Syndicated Local Dr. Mallika Marshall Local TV Tinnitus Source Type: news
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