Tetramethylpyrazine nitrone activates AKT/CREB through increasing BDNF expression to promote post ‐ischemic neuroregeneration and recovery of neurological functions in rats

Conclusion and ImplicationsTBN's ability to simultaneously provide neuroprotection and pro‐neurogenic effect may be a promising treatment for both acute phase neuroprotection and long‐term functional recovery after ischemic stroke.

Source: British Journal of Pharmacology - November 21, 2017 Category: Drugs & Pharmacology Authors: Gaoxiao Zhang, Tao Zhang, Ning Li, Liangmiao Wu, Jianbo Gu, Cuimei Li, Chen Zhao, Wei Liu, Luchen Shan, Pei Yu, Xifei Yang, Yaohui Tang, Guo ‐yuan Yang, Yuqiang Wang, Yewei Sun, Zaijun Zhang Tags: RESEARCH PAPER Source Type: research