GABA alterations in pediatric sport concussion

Conclusions: GABA/Cre appears increased in a region colocalized with working memory task activation after sport concussion. Further work extending these results in larger samples and at time points across the injury episode will aid in refining the clinical significance of these observations.
Source: Neurology - Category: Neurology Authors: Tags: fMRI, MRS, Adolescence, Brain trauma ARTICLE Source Type: research

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There has been lots of attention on concussions in youth, especially from sports, over the past few years. It’s good that we are paying more attention to concussions. As the stories of prior National Football League players show us, concussions can lead to lifelong problems. The problem for doctors, parents, and coaches has been that while we want to do the right thing when a child gets a concussion, we haven’t known what that right thing is. So it’s great news that the Centers for Disease Control and Prevention (CDC) has reviewed all the research and made recommendations to help guide us as we care for c...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Adolescent health Children's Health Concussions Parenting Source Type: blogs
For the first time, the Centers for Disease Control and Prevention  has issued guidelines for diagnosing and treating children who have suffered a concussion, also known as a mild traumatic brain injury. These guidelines will provide doctors with the tools they need to deliver the best outcomes for young patients with concussion, said two UCLA co-authors of the report, recently publish ed in JAMA Pediatrics.“Children have been overlooked in research and clinical protocols for concussion, but their smaller size doesn’t make them less important,” said Dr. Christopher Giza, director of the &nb...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
CONCLUSION: The diffusion phantom may be used to better elucidate inter-scanner variability in DTI-based measurement and provides an opportunity to better calibrate results obtained from scanners used in multisite and longitudinal studies. Novel solutions are being evaluated to understand and potentially overcome these differences. PMID: 30169993 [PubMed - in process]
Source: Brain Injury - Category: Neurology Tags: Brain Inj Source Type: research
In conclusion, I really enjoyed the opportunity to use the RightEye system. Working with Dr. Kungle and the RightEye system resulted in the most comprehensive, informative session I’ve ever had about my own vision and left me with clear areas t...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Neurology Neurosurgery Ophthalmology Source Type: blogs
Scientists at the Eunice Kennedy Shriver National Institute for Child Health and Human Development (NICHD) have developed a method implemented as pulse sequences and software to be used with magnetic resonance imaging (MRI) scanners and systems. This technology is available for licensing and commercial development. The method allows for measuring and mapping features of the bulk or average apparent diffusion coefficient (ADC) of water in tissue – aiding in stroke diagnosis and cancer therapy assessment. The pulse sequences and software enable MRI scanners to yield diffusion weighted images (DWI) that are orientationa...
Source: NIH OTT Licensing Opportunities - Category: Research Authors: Source Type: research
Are concerns about the brain health of professional athletes who played contact...Read more on AuntMinnie.comRelated Reading: Did PET scan confirm CTE in living NFL player? MRI shows football position, career length affect the brain MRI shows concussion effects can linger in athletes MRI shows promise in diagnosing CTE in living patients FDDNP-PET shows toll of concussions on retired NFL players
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
BETHESDA, Md.--BrainScope today announced its second consecutive nomination for the 2018 Annual Prix Galien USA Awards for “Best Medical Technology” product. Its flagship BrainScope One product is a multi-modal, comprehensive, handheld capability to help clinicians objectively and rapidly assess and triage head injured patients directly at the point of care. BrainScope’s innovative technology addresses a vast market need for the global epidemic of mild head injury, which impacts more people each year than stroke and heart failure combined. BrainScope One is the first FDA-cleared medica...
Source: JEMS: Journal of Emergency Medical Services News - Category: Emergency Medicine Authors: Tags: Trauma Product Announcements News Industry News Source Type: news
CONCLUSION: Microstructural alterations over the season and correlations with head impacts were captured by DKI metrics, which suggested that DKI imaging of gray matter may yield valuable biomarkers for evaluating brain injuries associated with subconcussive head impact. Findings in frontal cortical gray matter also indicated that contrecoup injury rather than coup injury might be the dominant mechanism underlying the observed microstructural alterations. ADVANCES IN KNOWLEDGE: Significant microstructural changes, as reflected by DKI metrics, in cortical gray matter such as the rostral middle frontal cortices, and in ...
Source: Neurobiology of Disease - Category: Neurology Authors: Tags: Neurobiol Dis Source Type: research
Publication date: Available online 21 July 2018Source: International Journal of PsychophysiologyAuthor(s): Erin D. Bigler, Chris Finuf, Tracy J. Abildskov, Naomi J. Goodrich-Hunsaker, Jo Ann Petrie, Dawn-Marie Wood, John R. Hesselink, Elisabeth A. Wilde, Jeffrey E. MaxAbstractThis investigation explored whether differences in cortical thickness could be detected in children who sustained a mild traumatic brain injury (mTBI) compared to those with orthopedic injury (OI) and whether cortical thickness related parental reporting of symptoms. To achieve this objective, FreeSurfer®-based cortical thickness measures were obt...
Source: International Journal of Psychophysiology - Category: Psychiatry & Psychology Source Type: research
ConclusionsResults from this pilot study suggest that early cognitive alterations and structural brain lesions affect a considerable percentage of patients with post-concussion syndrome following mTBI.ResumenIntroducciónLos traumatismos craneoencefálicos leves (TCE-L) han sido tradicionalmente considerados acontecimientos sin repercusiones cerebrales significativas, cuya sintomatología remite espontáneamente en unos días. Sin embargo, estos hechos son cada vez más cuestionados. Este estudio pretende objetivar la existencia de alteraciones cognitivas precoces en una serie de pacient...
Source: Neurologia - Category: Neurology Source Type: research
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