Immune systems and all that.

I guess I have a crappy immune system.... Or that's what they tell me. Nothing to do with cancer but that pesky chemo crap probably did something to my immune system during treatment. Now I have RA and the methotrexate definitely has messed up my immune system. Someone else's sniffles can make me sick for weeks.But I usually just ignore my immune system and do what I feel like. Call me a rule breaker if you want.When I was in chemo, they (the proverbial 'them') said I should avoid crowds and not to go to the mall, movie theaters etc. I didn't go to the mall or movie theaters. But I did work for the local community ed program in the office of a local high school. I am sure there are barely any germs in a high school. Just a few thousand teenagers. I wasn't concerned. I worked with a paranoid germaphobe and let her be concerned for me.This week I took my immune system compromised body through two airports (twice - there and back again (as Bilbo would say)) and sat in meeting rooms with other immune systems. I was probably exposed to about 10,000 other people, give or take 5,000. And I even rode the subway to minimize exposure.Now that I am home, I feel tired and my back hurts (that's nothing new there).I might have a sore throat but I am sure that is just be allergies. I'll may get to the the gym later. In the meantime I am doing many loads of laundry.
Source: Caroline's Breast Cancer Blog - Category: Cancer Tags: germs immune system travel Source Type: blogs

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Publication date: Available online 28 January 2020Source: Urology Case ReportsAuthor(s): Shinro Hata, Satoki AbeAbstractIn the Checkmate-025 trial, nivolumab treatment prolonged overall survival among patients with previously treated advanced renal cell carcinoma (RCC) compared with treatment with everolimus. Although effective, nivolumab is associated with immune-related adverse events (irAEs). However, the occurrence of hematological irAEs is rare. Some studies have reported on nivolumab-induced thrombocytopenia. Nivolumab associated thrombocytopenia in almost all patients improved with administration of various drugs. H...
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
We present the case of pre-operative pelvic lymph node sampling with the use of MRI/TRUS fusion-guided biopsy at the time of prostate biopsy. Lymph node pathology revealed metastatic, poorly differentiated prostate cancer, concurrent with Gleason 4+5 disease showing perineural invasion. The use of MRI fusion guided biopsy for nodal sampling may be an effective method pre-operative staging and treatment planning for prostate adenocarcinoma.
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
ConclusionsThese voting results from a panel of prostate cancer experts can help clinicians and patients navigate controversial areas of advanced prostate management for which high-level evidence is sparse. However, diagnostic and treatment decisions should always be individualised based on patient-specific factors, such as disease extent and location, prior lines of therapy, comorbidities, and treatment preferences, together with current and emerging clinical evidence and logistic and economic constraints. Clinical trial enrolment for men with advanced prostate cancer should be strongly encouraged. Importantly, APCCC 2019...
Source: European Urology - Category: Urology & Nephrology Source Type: research
Publication date: Available online 28 January 2020Source: Preventive MedicineAuthor(s): Elizabeth A. Sarma, Katharine A. Rendle, Sarah C. KobrinAbstractSymptom awareness may improve cancer outcomes by prompting timely help-seeking and diagnosis. Research in the UK has shown lower symptom awareness among sociodemographic groups at higher risk of poor cancer outcomes; however, no population-based surveys in the US have assessed whether cancer symptom awareness varies across sociodemographic groups. We therefore examined associations between sociodemographic factors and recognition of 11 cancer symptoms using a novel populati...
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: Available online 27 January 2020Source: Preventive MedicineAuthor(s): Nilofer S. Azad, Ira L. Leeds, Waruguru Wanjau, Eun J. Shin, William V. PadulaAbstractThe incidence of colorectal cancer (CRC) is increasing in patients under the age of 50. The purpose of this study was to assess the cost-utility of available screening modalities starting at 40 years in the general population compared to standard screening at 50 years old. A decision tree modeling average-risk of the CRC in the United States population was constructed for the cost per quality-adjusted life year (QALY) of the five most common and ef...
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: Available online 11 January 2020Source: European Journal of Surgical OncologyAuthor(s): Francesco Carli, Amal Bessissow, Rashami Awasthi, Sender LibermanAbstractThe elderly colorectal cancer patients tend to be frail, at nutrition risk with multiple comorbidities. In view of the stress on the body by surgery and recovery, it makes sense if patients are prepared before appropriately so that they can recover earlier and better. Prehabilitation prior to major surgery has attracted the attention of clinicians recently, and this review highlights the steps that need to be taken to implement a multidisciplinary...
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
hello i was wondering if anyone had heard back from the memorial sloan kettering cancer center (MSKCC) summer fellowship for 2020?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Medical Students - MD Source Type: forums
PMID: 31985642 [PubMed - in process]
Source: Hand Surgery - Category: Surgery Authors: Tags: Plast Reconstr Surg Source Type: research
CONCLUSIONS: Based on the available evidence, there is no increased risk of complications for elective hand surgery in patients with prior breast cancer treatment. Breast cancer patients with preexisting ipsilateral lymphedema carry slightly increased risk of postoperative infection and worsening lymphedema. It is the authors' opinion and recommendation that elective hand surgery with a tourniquet is not a contradiction in patients who have received previous breast cancer treatments. PMID: 31985641 [PubMed - in process]
Source: Hand Surgery - Category: Surgery Authors: Tags: Plast Reconstr Surg Source Type: research
Publication date: Available online 28 January 2020Source: Respiratory Medicine Case ReportsAuthor(s): Melinda Vasser, Matthew KoroscilAbstractBack pain is a common presenting concern in physician offices and emergency departments alike, with etiologies ranging from minor injuries to severe life-threatening illnesses. This case details the clinical course of a 68-year-old former smoker with no pulmonary symptoms who presented with back pain multiple times before developing cord compression syndrome and being diagnosed with non-small cell lung cancer (NSCLC). It demonstrates the importance of lung cancer screening and the ne...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
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