Biphasic Regulation of Spindle Assembly Checkpoint by Low and High Concentrations of Resveratrol Leads to the Opposite Effect on Chromosomal Instability

In conclusion, RSV exhibited a biphasic dose-dependent effect on CIN that was exerted via the regulation of mitotic fidelity through the SAC network. The health implications of these findings were summarized. Graphical abstract
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - Category: Genetics & Stem Cells Source Type: research