Anti-bacterial and anti-biofilm activity of commercial organic acid products against Salmonella enterica isolates recovered from egg farm environment.

This study evaluated the antibacterial activity of commercially available organic acid water additives against Salmonella enterica isolates and examined the susceptibility of Salmonella Typhimurium biofilms to these products. Three commercial organic acid products (A, B, and C) were evaluated for minimum inhibitory and bactericidal concentrations against isolates of S. enterica serovars. Three and five day old S. Typhimurium biofilms were formed at 22 ± 2°C using MBEC™ assay system and exposed for 30 and 90 min at 0.2 and 0.4% concentration. No significant difference among serovars for inhibitory and bactericidal concentrations was detected. Two products (A and C) significantly reduced viable cells from both ages of biofilms in a dose and time dependent manner. Increased biofilm age did not enhance resistance towards organic acid treatments. None of the products completely eliminated biofilm cells at any concentration or exposure time. Product composition, exposure time, and concentration of organic acid products were important factors in reducing viable biofilm cells. This study has expanded our understanding about the susceptibility of Salmonella biofilms to commercial organic acid products. These findings have implications in the usage, development, and optimization of organic acid products. PMID: 29058454 [PubMed - as supplied by publisher]
Source: Avian Pathology - Category: Pathology Authors: Tags: Avian Pathol Source Type: research