Treatment of orofacial granulomatosis: a case report

ConclusionsOur case questions whether granulomatous cheilitis really exists or is it simply a variant of Crohn ’s disease with only oral presentation. Our patient did not have symptoms of Crohn’s disease; moreover, endoscopic studies and computed tomography enterography were unremarkable for evidence of intestinal involvement. Our case is also the first reported case where high-dose infliximab alone has been used with sustained response for approximately 8 months. In conclusion, more research is needed to assess the underlying pathology as well as ideal treatment options for patients with orofacial granulomatosis. We propose that high-dose infliximab should be considered in patients who do not res pond to traditional therapies.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research