Rickettsial retinitis: Direct bacterial infection or an immune-mediated response ?

We report such a case of bilateral rickettsial retinitis proven by serology which worsened on systemic steroids and responded dramatically to therapy with oral doxycycline and steroid taper. We thus believe that direct bacterial invasion plays a major role in the pathogenesis of rickettsial retinitis.
Source: Indian Journal of Ophthalmology - Category: Opthalmology Authors: Source Type: research