The down-regulation of casein kinase 1 alpha as a host defense response against infectious bursal disease virus infection.

In conclusion, down-regulation of CK1α during IBDV infection as a host defense response increased abundance of IFNAR1, which in turn enhanced an inhibitory effect on IBDV replication.
PMID: 28988058 [PubMed - as supplied by publisher]

Source: Virology - October 4, 2017 Category: Virology Authors: Zhang L, Li H, Chen Y, Gao X, Lu Z, Gao L, Wang Y, Gao Y, Gao H, Liu C, Cui H, Zhang Y, Pan Q, Qi X, Wang X Tags: Virology Source Type: research