Benefit of dual-energy CT iodine overlay technique for T1-hyperintense brain lesion

A 47-year-old woman was admitted for radiation therapy of a left frontal glioblastoma, resected 2 months prior. On enhanced MRI, it was difficult to identify the tumor enhancement due to intrinsic T1 hyperintensity, possibly related to postoperative hemorrhage1 (figure, A–C). However, the iodine overlay image derived from the dual-energy CT technique (figure, D) was revealing: subsequent surgical resection confirmed residual tumor cells along the region that showed the elevated iodine concentration (figure, E). The dual-energy CT iodine overlay technique may be particularly useful in the evaluation of a T1-hyperintense lesion.2

Source: Neurology - September 25, 2017 Category: Neurology Authors: Lee, Y., Seo, H. S., Je, B.-K., Kim, S.-D., Oh, H. E. Tags: CT, MRI, Clinical neurology history, Primary brain tumor, Surgical therapy-tumor NEUROIMAGES Source Type: research