AGAR-BASED SCREENING FOR AZOLE RESISTANCE IN ASPERGILLUS FUMIGATUS USING VIPcheck ™: A SINGLE CENTRE EVALUATION.

Conclusion VIPcheck™ enabled selection of azole-resistant A. fumigatus colonies with a mean sensitivity and specificity of 0.98 and 0.93. Uninhibited growth on any azole-containing well after 24h and minimal growth after 48h were indicative of resistance. These results indicate that the VIPcheck™ is an easy-to-use tool for azole resistance screening and selection of colonies that require MIC-testing.
PMID: 28923874 [PubMed - as supplied by publisher]

Source: Antimicrobial Agents and Chemotherapy - September 18, 2017 Category: Microbiology Authors: Buil JB, van der Lee HAL, Rijs AJMM, Zoll J, Hovestadt JAMF, Melchers WJG, Verweij PE Tags: Antimicrob Agents Chemother Source Type: research