MRI substrates of sustained attention system and cognitive impairment in pediatric MS patients

Conclusions:
Our results suggest that the age-expected level of sustained attention system functional competence is achieved in patients with pediatric MS. Inefficient regulation of the functional interaction between different areas of this system, due to abnormal white matter integrity, may result in global cognitive impairment in these patients.

Source: Neurology - September 18, 2017 Category: Neurology Authors: De Meo, E., Moiola, L., Ghezzi, A., Veggiotti, P., Capra, R., Amato, M. P., Pagani, E., Fiorino, A., Pippolo, L., Pera, M. C., Comi, G., Falini, A., Filippi, M., Rocca, M. A. Tags: MRI, fMRI, Multiple sclerosis ARTICLE Source Type: research