High levels of macrolide-resistant Mycoplasma genitalium in Queensland, Australia.

High levels of macrolide-resistant Mycoplasma genitalium in Queensland, Australia. J Med Microbiol. 2017 Sep 12;: Authors: Trembizki E, Buckley C, Bletchly C, Nimmo GR, Whiley DM Abstract The macrolide azithromycin is recommended for treatment of Mycoplasma genitalium infection; however, M. genitalium strains possessing macrolide resistance-mediating mutations (MRMMs) are increasingly being reported. Here, we used the SpeeDx ResistancePlus MG kit, which provides simultaneous detection of M. genitalium and MRMMs, to assess MRMM carriage among M. genitalium infections in Queensland, Australia. Performance characteristics of the ResistancePlus MG kit for M. genitalium detection were compared to in-house PCR. Available M. genitalium PCR-positive (n=67) and negative (n=281) samples from the years 2011 to 2017 were tested using the SpeeDx ResistancePlus MG kit. In total, 63.6 % M. genitalium-positive samples were indicated to harbour MRMMs. The ResistancePlus MG method provided sensitivity and specificity of 97 and 99.6 % respectively compared to in-house PCR for M. genitalium detection. Such high levels of macrolide-resistant M. genitalium raise further concerns over future use of azithromycin for treatment of M. genitalium infection. PMID: 28893363 [PubMed - as supplied by publisher]
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research

Related Links:

Soft Matter, 2020, Accepted Manuscript DOI: 10.1039/D0SM00959H, PaperNoohul Alam, Debajit Sarma Sequestration of hazardous radioactive iodine and dye separation to reduce industrial waste through reutilization is pivotal for environmental safety. In this regard, herein, synthesis of a new waterborne ultrasensitive supramolecular... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Soft Matter latest articles - Category: Chemistry Authors: Source Type: research
Soft Matter, 2020, Accepted Manuscript DOI: 10.1039/D0SM01303J, PaperTingyuan Tan, Zhiwei Shen, Yujiao Wang, Zhen Guo, Jun Hu, Yi Zhang organogels have a wide variety of applications in the fields of chemistry, electricity, biomedicine and environmental engineering, which call for robust strategies for designing and developing novel organogelators. Here, we... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Soft Matter latest articles - Category: Chemistry Authors: Source Type: research
Soft Matter, 2020, Accepted Manuscript DOI: 10.1039/D0SM01474E, PaperHongyu Guo, Qi Yu, Yuzhi Xiong, Fafu Yang Although various AIE liquid crystals had been studied, the AIE ionic liquid crystal (ILC) was almost unknown up to date. In this work, series of novel AIE ILCs based on... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Soft Matter latest articles - Category: Chemistry Authors: Source Type: research
Soft Matter, 2020, Accepted Manuscript DOI: 10.1039/D0SM01473G, PaperSonja Dieterich, Sylvain Prevost, Carina Dargel, Thomas Sottmann, Frank Giesselmann In this work we present a systematic study on the microstructure of soft materials which combine the anisotropy of lyotropic liquid crystals with the mechanical stability of a physical gel.... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Soft Matter latest articles - Category: Chemistry Authors: Source Type: research
Phys. Chem. Chem. Phys., 2020, Accepted Manuscript DOI: 10.1039/D0CP04349D, PerspectiveWolfgang E Ernst, Andreas Wolfgang Hauser Metal clusters have drawn continuous interest because of their high potential for the assembly of matter with special properties that may significantly differ from the corresponding bulk. Controlled combination of... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - Category: Chemistry Authors: Source Type: research
Phys. Chem. Chem. Phys., 2020, Accepted Manuscript DOI: 10.1039/D0CP04407E, PaperSo Young Eom, Yu Ran Lee, Chan Ho Kwon Piperidine has received attention in pharmaceutical synthesis and biochemical degradations because of its conformational activity. We explored the conformational structures of piperidine in the neutral (S0) and cationic (D0) ground... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - Category: Chemistry Authors: Source Type: research
Phys. Chem. Chem. Phys., 2020, Accepted Manuscript DOI: 10.1039/D0CP04397D, PaperKavya Bhakuni, Niketa Yadav, Pannuru Venkatesu Proteins have immense untapped potential in numerous industries as a green catalyst. Thus, there is an emergent need to find a suitable co-solvent that is biocompatible with protein and environmentally... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - Category: Chemistry Authors: Source Type: research
Phys. Chem. Chem. Phys., 2020, Accepted Manuscript DOI: 10.1039/D0CP03883K, PaperZhiling Liu, Yan Bai, Ya Li, Jing He, Qingyang Lin, Hua Xie, Zichao Tang The homoleptic homodinuclear nickel carbonyl anions Ni2(CO)n− (n = 4 −6) are mass-selected in the gas phase and examined with anion photoelectron velocity-map imaging spectroscopy combined with the density functional calculations.... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - Category: Chemistry Authors: Source Type: research
Phys. Chem. Chem. Phys., 2020, Accepted Manuscript DOI: 10.1039/D0CP03800H, PaperZhifan Wang, Minggang Guo, Fan Wang It has been shown that coupled-cluster calculations with single-precision data are able to provide correlation energy with insignificant loss of accuracy. In this work, we employed consumer GPUs to accelerate... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - Category: Chemistry Authors: Source Type: research
Phys. Chem. Chem. Phys., 2020, Accepted Manuscript DOI: 10.1039/D0CP03994B, PaperStuart Brown, Calum J Drummond, Jessica Marchand, Sebastian Marcuccio, Kieran Stockton, Tamar Louise Greaves While there have been many studies on the physicochemical characterisation of ILs, little work has previously been reported on the properties unique to the trifluoroborate anion. Here we have characterised... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - Category: Chemistry Authors: Source Type: research
More News: Australia Health | Azithromycin | Marketing | Microbiology | Zithromax