Predictors of granulomatous lymphocytic interstitial lung disease in common variable immunodeficiency: Methodological issues

We read with great interest the article by Hartono et  al1 that was published in the Annals of Allergy, Asthma& Immunology in May 2017. They intended to determine a set of clinical and/or laboratory parameters associated with granulomatous lymphocytic interstitial lung disease (GLILD). Based on univariable analysis, they stated that splenomegaly was independently associated with GLILD (odds ratio [OR] 17.3, 95% confidence interval [CI] 3.9 –74.5). Although the study was useful and very interesting, some methodologic issues need to be considered.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Correspondence Source Type: research