Clinical grade manufacturing of genetically modified, CAR-expressing NK-92 cells for the treatment of ErbB2-positive malignancies

ConclusionOur concept suggests NK-92/5.28.z maintenance culture from which therapeutic doses up to 5  × 109 cells can be expanded in 10  L within 5 days. This established process is feasible to analyze NK-92/5.28.z in phase I/II trials.
Source: Cancer Immunology, Immunotherapy - Category: Cancer & Oncology Source Type: research