Comprehensive Guidance for Antibiotic Dosing in Obese Adults

ConclusionsAdditional studies are needed to better understand and resolve discrepant published results regarding the PK of antibiotics in order to establish optimal dosing strategies in obese adults. Alternative dosing strategies, such as extended infusions, should be considered for time‐dependent antibiotics (e.g. β‐lactams) in obese patients to reliably achieve pharmacodynamics targets. Therapeutic drug monitoring across the spectrum of antimicrobials is of increasing importance in this and other populations in order to assure optimized dosing.This article is protected by copyright. All rights reserved.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - Category: Drugs & Pharmacology Authors: Tags: Review of Therapeutics Source Type: research