Targeting CCl4 ‐induced liver fibrosis by RNA interference–mediated inhibition of cyclin E1 in mice

Conclusion: Therapeutic targeting of CcnE1 in vivo using RNAi is feasible and has high antifibrotic activity. (Hepatology 2017).

Source: Hepatology - August 26, 2017 Category: Internal Medicine Authors: J örg‐Martin Bangen, Linda Hammerich, Roland Sonntag, Maike Baues, Ute Haas, Daniela Lambertz, Thomas Longerich, Twan Lammers, Frank Tacke, Christian Trautwein, Christian Liedtke Tags: Liver Injury and Regeneration Source Type: research