A state-independent network of depressive, negative and positive symptoms in male patients with schizophrenia spectrum disorders

Depressive symptoms occur frequently in patients with schizophrenia. Several factor analytical studies investigated the associations between positive, negative and depressive symptoms and reported difficulties differentiating between these symptom domains. Here, we argue that a network approach may offer insights into these associations, by exploring interrelations between symptoms. The aims of current study were to I) construct a network of positive, negative and depressive symptoms in male patients with schizophrenia to investigate interactions between individual symptoms; II) identify the most central symptoms within this network and III) examine group-level differences in network connectivity between remitted and non –remitted patients.

Source: Schizophrenia Research - August 23, 2017 Category: Psychiatry Authors: Geeske van Rooijen, Adela-Maria Isvoranu, Olle H. Kruijt, Claudia D. van Borkulo, Carin J. Meijer, Johanna T.W. Wigman, Henricus G. Ruh é, Lieuwe de Haan, GROUP investigators Source Type: research