Uncommon Occurrence of Lip Squamous Cell Carcinoma in a Pediatric Patient
ConclusionsHPV prevalence in the oral mucosa of the assessed FA patients was higher than reported in the general population. Additional studies with collection of sequential samples are needed to know the natural history of the presence of multiple HPV types in these individuals and its association with the development of tumors, to evaluate the implementation of preventive measures, such as vaccination, and to guide early treatment.This article is protected by copyright. All rights reserved.
Publication date: February 2019Source: Oral and Maxillofacial Surgery Clinics of North America, Volume 31, Issue 1Author(s): Payam Afzali, Brent Benson Ward
CONCLUSIONS: The above method is a valid alternative to methods already in use. The results obtained demonstrate the efficacy and tolerability of the treatment described which, due to its versatility and speed of use, is preferable to the methods used so far. PMID: 30428649 [PubMed - as supplied by publisher]
This study is registered with ClinicalTrials.gov, number NCT01302834.FindingsBetween June 9, 2011, and July 31, 2014, 987 patients were enrolled, of whom 849 were randomly assigned to receive radiotherapy plus cetuximab (n=425) or radiotherapy plus cisplatin (n=424). 399 patients assigned to receive cetuximab and 406 patients assigned to receive cisplatin were subsequently eligible. After median follow-up duration of 4·5 years, radiotherapy plus cetuximab did not meet the non-inferiority criteria for overall survival (hazard ratio [HR] 1·45, one-sided 95% upper CI 1·94; p=0·5056 for non-inferior...
CONCLUSIONS: MI-ILP is feasible and gives the same treatment characteristics as open ILP, but with the advantage of a minimally invasive vascular access. PMID: 30428725 [PubMed - as supplied by publisher]
We examined 102 patients with Wang T1-T2 squamous cell carcinoma of the nasal vestibule to assess local-regional control rates and patient satisfaction after image guided brachytherapy. Furthermore, tumor volume was explored as prognostic factor for recurrence. We found that brachytherapy offers excellent local control with high patient satisfaction. Tumor volume was found to be an adequate predictive factor for patients at risk of regional recurrence.
Authors: Shao EX, Carew B, Muir J PMID: 30428823 [PubMed - in process]
Pathway analysis of a genome‑wide association study on a long non‑coding RNA expression profile in oral squamous cell carcinoma. Oncol Rep. 2018 Nov 15;: Authors: Qiu YL, Liu YH, Ban JD, Wang WJ, Han M, Kong P, Li BH Abstract Long non‑coding RNAs (lncRNAs) have been consistently demonstrated to be involved in oral squamous cell carcinoma (OSCC) as either tumor oncogenes or tumor suppressors. However, the underlying mechanisms of OSCC tumorigenesis and development have not yet been fully elucidated. The expression profiles of mRNAs and lncRNAs in OSCC were analyzed by a microarray assay. To verify...
Authors: Zhao L, Chi W, Cao H, Cui W, Meng W, Guo W, Wang B Abstract In order to identify potential diagnostic and prognostic biomarkers, and treatment targets for head and neck squamous cell carcinoma (HNSCC), the present study obtained the gene expression profiles in HNSCC through public data mining, and core genes were identified using a series of bioinformatics analysis methods and databases. A total of nine hub genes (SPP1, ITGA6, TMPRSS11D, MMP1, LAMC2, FAT1, ACTA1, SERPINE1 and CEACAM1) were identified to be significantly correlated with HNSCC. Furthermore, overall survival analysis demonstrated that the exp...
Condition: Head and Neck Squamous Cell Carcinoma Intervention: Drug: Anti-EGFR monoclonal antibody Sponsor: Shi Yuankai Not yet recruiting