Uncommon Occurrence of Lip Squamous Cell Carcinoma in a Pediatric Patient
CONCLUSIONS: MiR-601 suppressed the proliferation, invasion and migration of esophagus carcinoma cells by down-regulating HDAC6 expression. PMID: 30779074 [PubMed - in process]
Conclusions Switch maintenance therapy with S-1 after induction therapy with carboplatin andnab-paclitaxel was associated with moderate efficacy and acceptable safety and may represent a feasible treatment option for patients with advanced SCC.
CONCLUSIONS circ_0067934 could improve the development of thyroid carcinoma by promoting EMT and PI3K/AKT signaling pathways. PMID: 30779728 [PubMed - in process]
This study was developed with the objectives of evaluating the relationship between HPV and oral and oropharyngeal squamous cell carcinomas (OOSCC), and of studying the correlation between HPV detection tests (PCR and p16). MATERIAL AND METHOD: Retrospective study of patients treated for OOSCC during 2011, with a follow-up of 6 years. The sample was divided into 2 groups according to HPV positivity, detected by 2 techniques: p16 by immunohistochemistry and PCR. Demographic and clinical variables were analysed using SPSS® 22.0, considering P
Publication date: April 2019Source: Biomedicine &Pharmacotherapy, Volume 112Author(s): Donglei Liu, Min Gao, Kai Wu, Dengyan Zhu, Yang Yang, Song ZhaoAbstractLong non-coding RNAs (LncRNAs) have been found to be associated with the biological behaviors of human cancers. LINC00152 is reported as an oncogene in many kinds of malignancies. However, the functions and mechanisms of LINC00152 involved in esophageal squamous cell carcinoma (ESCC) remain elusive. Our results revealed that LINC00152 expression was up-regulated in ESCC, and correlated with advanced TNM stage, lymph node metastasis, and poor prognosis of ESCC pati...
Hematopoietic stem cell transplantation (HCT), which is increasingly used to treat patients with malignant and non-malignant conditions, is associated with increased risk for malignancies, including skin cancers. Data on incidence is incomplete, however, as more recent practices have utilized different donor sources and reduced-intensity conditioning regimens. In a contemporary cohort of 1,974 allogeneic HCT patients, Wu and colleagues found significantly increased incidences of basal cell carcinoma, squamous cell carcinoma, and melanoma.
ConclusionsH3K9me3, H4K20me3, and H3K36me3 showed a close relationship with clinical features and were considered independent risk factors for survival of ESCC patients. The combination of H3K9me3, H4K20me3, and H3K36me3 expression, rather than the expression of a single histone marker, is believed to further enhance evaluations of ESCC prognosis and management.
Publication date: March 2019Source: European Journal of Obstetrics &Gynecology and Reproductive Biology, Volume 234Author(s): Hamza Guennoun, Ahmed Guennoun, Yousra Krimou, Beya Mahmoud, Sanaa Errarhay, Sanaa Errarhay, Chahrazed Bouchikhi, Abdelaziz Banani
Introduction: Squamous cell carcinoma (SCC) of the vulva recurrences vary considerably over time and are influenced by several pathological, surgical and adjuvant therapeutic prognostic factors. However, limited information is available about patterns of disease recurrence and prognosis.
Introduction: Although the incidence of cervical carcinoma decreased, the incidence of cervical adenocarcinoma (AC) was reported to increase compared to squamous cell carcinoma (SCC) Histology of adenocarcinoma was reported to have poor prognostic both in early and advanced cervical cancer in some reports.