The role of avian reoviruses in turkey tenosynovitis/arthritis.

The role of avian reoviruses in turkey tenosynovitis/arthritis. Avian Pathol. 2014 Jul 1;:1-29 Authors: Sharafeldin TA, Mor SK, Bekele AZ, Verma H, Goyal SM, Porter RE Abstract Turkey arthritis reovirus (TARV) has been isolated from the gastrocnemius tendons and tibiotarsal joint fluid of lame, >12-week-old male turkeys in the Midwest. Two experiments were conducted to compare the pathogenicity in turkeys of three TARVs (TARV-MN2, TARV-MN4 and TARV-O'Neil) one turkey enteric reovirus (TERV strain MN1), and one chicken arthritis reovirus (CARV strain MN1). Two hundred ul of virus were inoculated by oral, intratracheal, or footpad route into 6-day-old poults placed in isolator units. Poults were necropsied at 1 and 4 weeks post infection (PI) in Experiment 1 and at 2 and 4 weeks PI in Experiment 2. Reovirus was detected by RT-PCR and virus isolation in tendons of TARV-inoculated poults at 1, 2 and 4 weeks PI. In general, TARVs produced lymphocytic tenosynovitis of the gastrocnemius and digital flexor tendon sheaths without inflammation of the tendons proper. In Experiment 1, poults inoculated with TARV-MN2 and TARV-O'Neil had significantly higher gastrocnemius tendon inflammation scores, as determined by histology, than those inoculated with TERV-MN1 or CARV-MN1. In Experiment 2, poults inoculated with TARV-MN2 and TARV-O'Neil had significantly higher gastrocnemius tendon inflammation scores than those inoculated with TARV-MN4 and v...
Source: Avian Pathology - Category: Pathology Authors: Tags: Avian Pathol Source Type: research