Inhibitory effect of ent-Sauchinone on amyloidogenesis via inhibition of STAT3-mediated NF-kappaB activation in cultured astrocytes and microglial BV-2 cells

Conclusions: These results indicated that ent-Sauchinone inhibited neuroinflammation and amyloidogenesis through the inhibition of STAT3-mediated NF-kappaB activity, and thus could be applied in the treatment of neuro-inflammatory diseases, including Alzheimer's disease.

http://www.jneuroinflammation.com/content/11/1/118

Source: Journal of Neuroinflammation - July 2, 2014 Category: Neurology Authors: Suk-Young SongYu JungChul HwangHee LeeChang SokJoo KimSang LeeHyun SeoByung HyunDong ChoiSang HanYoung HamBang HwangJin Hong Source Type: research

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