Conditioned pain modulation is affected by occlusion cuff conditioning stimulus intensity, but not duration

ConclusionsThis study demonstrated that an occlusion cuff of 5/10 conditioning stimulus intensity, when compared to 2/10, significantly increased CPM magnitude. Maintaining 2/10 conditioning stimulus for 3 min did not increase CPM magnitude.
SignificanceDysfunctional conditioned pain modulation (CPM) has been associated with poor health outcomes. Various factors can influence CPM outcomes. The role of occlusion cuff conditioning stimulus intensity and duration has not been previously investigated. Intensity (5/10), but not duration of lower intensity (2/10) conditioning stimulus, affects CPM magnitude.

Source: European Journal of Pain - August 14, 2017 Category: Anesthesiology Authors: A. Smith, A. Pedler Tags: Original Article Source Type: research