Microsaccade dysfunction and adaptation in hemianopia after stroke.

Microsaccade dysfunction and adaptation in hemianopia after stroke. Restor Neurol Neurosci. 2017;35(4):365-376 Authors: Gao Y, Sabel BA Abstract BACKGROUND: Besides the reduction of visual field size, hemianopic patients may also experience other poorly understood symptoms such as blurred vision, diplopia, or reduced visual acuity, which may be related to microsaccade function. OBJECTIVE: To determine (i) if microsaccades are altered in hemianopia; (ii) how altered microsaccade features correlate with visual performances; and (iii) how their direction relates to visual field defect topography. METHODS: In this case-control study, microsaccades of hemianopic stroke patients (n = 14) were assessed with high-resolution eye-tracking technique, compared with those of healthy controls (n = 14), and correlated with visual performances, visual field defect parameters and lesion age. RESULTS: Patients' microsaccades had (i) larger amplitude (P = 0.027), (ii) longer duration (P = 0.042), and (iii) impaired binocular microsaccade conjugacy (horizontal: P = 0.002; vertical: P = 0.035). Older lesions were associated with poorer binocular conjugacy (horizontal: r(14) = 0.67, P = 0.009; vertical: r(14) = 0.75, P = 0.002) and larger microsaccade amplitudes (r(14) = 0.55, P = 0.043). (iv) Half of the patients had a microsaccade bias towards the seeing field (monocular: P = 0.002; binocular: P 
Source: Restorative Neurology and Neuroscience - Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

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Publication date: Available online 14 September 2019Source: Journal of Vascular and Interventional RadiologyAuthor(s): David L. Dornbos, Shahid M. Nimjee, Tony P. SmithAbstractInadvertent arterial placement of central venous catheters carries serious sequelae, including pseudoaneurysm development and stroke. Although numerous strategies for therapeutic repair after arterial injury have been employed, no treatment provides a definitive standard of care. All articles published between January 2000 and July 2018 involving the placement of central venous catheters in the brachiocephalic or subclavian arteries, carotid artery, ...
Source: Journal of Vascular and Interventional Radiology - Category: Radiology Source Type: research
ConclusionCollectively our data suggest that the bioactive chemical pool which is responsible for the therapeutic effects of EW can be extracted in petroleum ether, and fractionated to a relatively small multiple components. Such components include known anti-inflammatory chemicals, which may contribute to the possible microglia polarization in brain lesion during the recovery of ischemic stroke.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
ConclusionThe present method did not only preliminarily reveal the active substances and mechanism of NAC in treatment of IS from the perspective of network pharmacology, but show its potential application for research and development of other TCM prescriptions.
Source: European Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
ConclusionUsing NMA, this study will offer new and informative evaluations of current TCPMs for ACI. The results will inform clinicians, provide optimal clinical treatment strategies, bridge the evidence gaps, and identify promising TCPMs for evaluation in future trials.The protocol has been registered on PROSPERO (International Prospective Register of Systematic Reviews) (CRD42018110307).
Source: European Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
Anti-inflammatory compounds from this delicious food dampen the risk of heart disease and stroke. → Support PsyBlog for just $4 per month. Enables access to articles marked (M) and removes ads. → Explore PsyBlog's ebooks, all written by Dr Jeremy Dean: Accept Yourself: How to feel a profound sense of warmth and self-compassion The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything Activate: How To Find Joy Again By Changing What You Do
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Psychology Source Type: blogs
Publication date: Available online 14 September 2019Source: Biochimica et Biophysica Acta (BBA) - General SubjectsAuthor(s): James J. Miller, Adam J. Kanack, Nancy M. DahmsAbstractBackgroundFabry disease is caused by α-galactosidase A deficiency. Substrates of this lysosomal enzyme accumulate, resulting in cellular dysfunction. Patients experience neuropathic pain, kidney failure, heart disease, and strokes.Scope of reviewThe clinical picture and molecular features of Fabry disease are described, along with updates on disease mechanisms, animal models, and therapies.Major conclusionsHow the accumulation of α-ga...
Source: Biochimica et Biophysica Acta (BBA) General Subjects - Category: Biochemistry Source Type: research
In this study, researchers studied 438,952 participants in the UK Biobank, who had a total of 24,980 major coronary events - defined as the first occurrence of non-fatal heart attack, ischaemic stroke, or death due to coronary heart disease. They used an approach called Mendelian randomisation, which uses naturally occurring genetic differences to randomly divide the participants into groups, mimicking the effects of running a clinical trial. People with genes associated with lower blood pressure, lower LDL cholesterol, and a combination of both were put into different groups, and compared against those without thes...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
PMID: 31519132 [PubMed - in process]
Source: Clinical Rehabilitation - Category: Rehabilitation Authors: Tags: Clin Rehabil Source Type: research
We all have strong emotions from time to time. We have all had that experience of feeling “emotionally hijacked” in which we feel powerless against the influence our emotions have on our behavior, mood, and general perspective. Strong emotions can prompt powerful thoughts, and sometimes, repetitive thoughts. If we are struggling with a persistent emotion, it can be difficult to put the feeling down or let it go. We carry the worry with us day and night.  But if we can remove ourselves from the subjective experience of any given emotion, we might be able to size up its impact on our lives a little more real...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Mindfulness Personal Self-Help anxiety Fear Rumination stress reduction Worry Source Type: blogs
Photo credit Yoann Boyer Dear Carol: I was widowed young and had no children so when my mother had her first stroke in her 80s I moved her in with me. I recently remarried and my new husband’s fine with mom living with us since we have a large home, but problems are coming up and I feel torn. My husband wants us to travel some, and I want this, too. He’s good to Mom, but soon his resentment about us being tied down is bound to show in how he relates to her. Mom doesn’t want to go to a care facility because she says that they cost too much and she wants to leave her money to my brothers and me. I tell...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
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