Increasing Frequency of Diagnosis of Transthyretin Cardiac Amyloidosis and Changing Survival Over Time

Background: Cardiac amyloidosis is a group of rare diseases resulting from extracellular deposition of amyloid protein, principally due to light chain (AL) amyloid or acquired or hereditary changes in TTR protein. Transthyretin cardiac amyloidosis (TTR) is increasingly recognized as an important cause of heart failure with preserved ejection fraction; the frequency of diagnosis has noted to be increasing. We aimed to investigate the changing phenotype and survival over time of patients diagnosed with cardiac amyloidosis at the Center for Advanced Cardiac Care (CACC).

Source: Journal of Cardiac Failure - August 1, 2017 Category: Cardiology Authors: Hannah Rosenblum, Adam Castano, Julissa Alvarez, Stephen Helmke, Mathew S. Maurer Source Type: research