The Duffy null genotype is associated with a lower level of CCL2, leukocytes and neutrophil count but not with the clinical outcome of HTLV-1 infection.

CONCLUSION: We conclude that although the Duffy null genotype was associated with leukopenia, neutropenia and lower levels of CCL2, the data do not suggest the influence of Duffy genotypes on the neurologic outcome of HTLV-1 infection, but may be a confounding factor in comparison HTLV-1-infected populations with different ancestries, especially when defining inflammatory biomarkers.
PMID: 28771137 [PubMed - as supplied by publisher]

Source: Journal of Medical Microbiology - August 4, 2017 Category: Microbiology Authors: da Silva-Malta MCF, Sales CC, Guimarães JC, de Cássia Gonçalves P, Chaves DG, Santos HC, da Costa Pereira A, Ribas JG, de Freitas Carneiro-Proietti AB, Martins ML Tags: J Med Microbiol Source Type: research