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Accuracy of a Laryngopharyngeal Endoscopic Esthesiometer (LPEER) for Evaluating Laryngopharyngeal Mechanosensitivity: A Validation Study in a Prospectively Recruited Cohort of Patients

AbstractRecent studies have shown an association between alterations in laryngopharyngeal mechanosensitivity (LPMS) and dysphagia, obstructive sleep apnea, and chronic cough hypersensitivity syndrome. A previous reliability study of a new laryngopharyngeal endoscopic esthesiometer and rangefinder (LPEER) showed high intra- and inter-rater reliability; however, its accuracy has not been tested. We performed an accuracy study of the LPEER in a prospectively and consecutively recruited cohort of 118 patients at two tertiary care university hospitals. Most of the patients were suffering from dysphagia, and all of them underwent a standard clinical evaluation and fiberoptic endoscopic evaluation of swallowing with sensory testing (FEESST) using a new sensory testing protocol. The sensory test included determinations of the laryngeal adductor reflex threshold (LART), the cough reflex threshold (CRT) and the gag reflex threshold (GRT). Abnormalities on these reflex thresholds were evaluated for associations with major alterations in swallowing safety (pharyngeal residues, penetration, and aspiration). We evaluated the discriminative capacity of the LPMS test using ROC curves and the area under the curve (AUC –ROC) and its relationship with the eight-point penetration–aspiration scale (PAS) using the Spearman’sρ correlation coefficient (SCC). We found a positive correlation between the PAS and LART (SCC 0.47;P 
Source: Dysphagia - Category: Speech-Language Pathology Source Type: research

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Abstract Swallowing reflex is known to be evoked by gastroesophageal regurgitation or esophageal stimulation in animal studies. However, details regarding the stimulating material, bolus size, and stimulation area remain unclear for the stimulationā€induced type of swallowing reflex in human. Here, we evaluated the effects of different kinds of stimulation via water and air injection of the esophagus on the initiation of the swallowing reflex. Nine healthy individuals participated in this study. A fiberoptic endoscope was passed transnasally and a thin catheter for injection was passed through the other side. The tip of t...
Source: Journal of Oral Rehabilitation - Category: Dentistry Authors: Tags: Original Article Source Type: research
There many, many articles and books on living simply. Some pieces recommend getting rid of (almost) everything you own. Others focus on frugal living. Still others suggest skipping cell phones and social media, growing your own food, and giving away your car and TV. Sometimes, we also get the impression that living simply is a sacrifice, according to author and blogger Courtney Carver. Because, well, you love your car, and you love your TV. And maybe you want to have a closet full of clothes, even if you only wear many of them for special occasions. Maybe you want a huge house. Maybe you love your extensive book collection...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Habits Happiness Mental Health and Wellness Motivation and Inspiration Relationships Self-Help Stress Success & Achievement Habit Change humble minimalism minimalist simplify Source Type: blogs
By SHANNON HALLOWAY &MELISSA KALENSKY A patient walked into clinic wearing only a hospital gown, feet bare and EKG wires trailing. Just hours after having surgery, his dementia had prompted him to wander out of the hospital and walk two miles to proudly show off his new surgical scar to a familiar face. Physically unharmed, his heart was easy to fix but his memory was beyond repair. Though the road to a cure has long seemed insurmountable, dementia advocates have recently found reason to celebrate. Scientists announced this week the development of a new tool that may help identify people who are prone to Alzheimer&rsqu...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Uncategorized Alzheimer's Dementia prevention Source Type: blogs
The effect runs in the family. *** ~ THE EBOOKS ~ Escape from low mood or depression with my "Activate ebook" Discover how to deal with anxiety in my "Anxiety plan ebook" Boost your motivation for anything with my "Spark ebook" by Dr JEREMY DEAN ***
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Depression Source Type: blogs
No one starts off in life wanting to worry about money. In fact, most of us dream of achieving wonderful things, including the ability to buy what we want, when we want it. It’s only after a series of disappointments — some call them hard knocks — that we come to the realization that money only goes so far. If we fail to learn the lessons of budgeting and saving, we’re destined to keep running into financial problems. This can lead to many a sleepless night, accompanied by worry and depression about finances. Finding a path from what I’ll call financial illiteracy to being more financially sav...
Source: Psych Central - Category: Psychiatry Authors: Tags: Anxiety Depression Money and Financial finances Financial Burdens money problems spending Source Type: news
Authors: Riem N PMID: 29243448 [PubMed - as supplied by publisher]
Source: Minerva Anestesiologica - Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research
Authors: Rodrigues R, Franke RA, Teixeira BC, Macedo RCO, Lopes AL, Reischak-Oliveira Á, Baroni BM, Vaz MA Abstract Alcohol intake and sleep deprivation are conditions that cause changes in the physiological status. However, the relationship between biological markers and mood states is not entirely clear yet. The purpose of the study was to compare isolated and combined effects of alcohol intake and sleep deprivation on hormonal and inflammatory responses and in changes in the state of mood. Also, we intended to explain possible changes in mood states through biochemical variations using multiple stepwise r...
Source: The Chinese Journal of Physiology - Category: Physiology Tags: Chin J Physiol Source Type: research
HEARTBURN symptoms include nausea and difficulty swallowing. Combat the pain while sleeping by making these changes to your diet.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
2017 will be remembered for the substantial progress related to therapeutic approaches in the neuromuscular field. Selecting just a few studies to highlight is quite challenging because many has been reported, from observations of innovative therapeutic approaches in animal studies to the results of successful clinical trials. Perhaps the most exciting of these advances have been in Duchenne muscular dystrophy and spinal muscular atrophy.
Source: Lancet Neurology - Category: Neurology Authors: Tags: 2017 Round-up Source Type: research
CONCLUSIONS: The propofol-remifentanil combination was associated with a higher incidence of desaturation. The dexmedetomidine-remifentanil combination was associated with inadequate sedation in one half of the patients, even though it produced less respiratory depression. Addition of remifentanil reduced the cough reflex. PMID: 25643766 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - Category: Sleep Medicine Authors: Tags: Sleep Breath Source Type: research
More News: Cough | Hospitals | Obstructive Sleep Apnea | Reflex Sympathetic Dystrophy | Sleep Apnea | Sleep Disorders | Sleep Medicine | Speech-Language Pathology | Study