Free Fatty Acid Is Associated with Thrombogenicity in Cardioembolic Stroke

Background: Recently, the role of free fatty acids (FFAs) in thromboembolism has re-emerged in the context of cardioembolic stroke. Therefore, we attempted to determine the role of FFAs in embolic risk in various potential sources of cardioembolism (PSCE). We hypothesized that if elevated FFA levels in stroke patients are associated with thrombogenesis, then patients with a well-known high risk of embolic sources would have high FFA levels.Methods: Data collected from 2 hospital-based stroke registries were analyzed to investigate the association between FFA and PSCE.Results: A total of 2,770 acute stroke patients, including 539 with cardioembolic stroke, were selected for analysis. FFA was an independent predictor for cardioembolism (OR 2.755, 95% CI 2.221-3.417,p
Source: Cerebrovascular Diseases - Category: Neurology Source Type: research