Age at diagnosis and gender modify the risk of 9q22 and 14q13 polymorphisms for papillary thyroid carcinoma.

CONCLUSIONS: the association between PTC and all analysed SNPs was confirmed. It was also shown that patient-related factors modify the predisposition to PTC by increasing the risk for rs944289 per year of age, and by enhancing the protective effect of the FOXE1 GGT haplotype in men.
PMID: 28660995 [PubMed - in process]

Source: Endokrynologia Polska - July 1, 2017 Category: Endocrinology Authors: Kula D, Kalemba M, Puch Z, Polańska J, Świerniak M, Rusinek D, Żebracka-Gala J, Kowalska M, Handkiewicz-Junak D, Kowal M, Tyszkiewicz T, Piasna E, Czarniecka A, Pawlaczek A, Krajewska J, Szpak-Ulczok S, Jarząb B Tags: Endokrynol Pol Source Type: research